High Performance Genomic Engine
The GQ-Engine is purpose-built to manage, analyze, and interpret genomic sequences and annotations at whole/multi-genome scale and across all samples and reference datasets.
The core technology was started by the company’s Chief Scientific Officer Dr. Jean-Jacques Codani, in the 1990s to support the Human Genome Project. Since then, he and his French team have contributed more than 150 man-years of Computer Science and Molecular Biology expertise to advancing its market-leading, high-performance capabilities, including:
- Comparison and management of genomic sequences with native database-to-database compare
- A unified sequence and annotation data model
- Multi-algorithm alignment and comparison including gapped, non-gapped, and local/global alignments
- Universal support for all sequencing platforms and inherent support for SAM/BAM
- “Embarrassingly parallel”: multi-threaded and distributed
- Interactive sequence/result querying, sorting, grouping, formatting, and saving
- Results reusable as input sequence databases
- Linkable databases: viewing multiple databases as one virtual database
- A complete and expressive scripting language, designed for genomics
- Co-developed software/hardware architecture with SGI that offers genome-center scale and whole/multi-genome analysis
GenomeQuest’s hosting architecture presently has capacity for processing 150 genomes per month, and will soon be scaling to thousands of genomes per month. It features:
- Multiple, load-balanced head nodes to service high-volume user requests and interactions
- Rackable® XE, server stack of high-performance compute nodes to service highly-parallelized, sequence database comparisons
- Storage solution featuring high-performance I/O subsystem scalable to Petabytes
- Housed in a Type II SAS 70 compliant data center with fully redundant hardware and software for 24/7 availability
All GenomeQuest capabilities are available as a hosted service running on the GenomeQuest data center or deployed on an organization’s data center behind their firewall.
Hosting Architecture
Tiered Software Platform Built on the GQ-Engine
